Testing age as a moderator of the relationship between depression and healthy functioning in breast and gynecologic cancer patients
Abstract
This cross-sectional study aims to explore age as a moderator of the association between emotional distress and functional scales of health-related quality of life. The sample includes 106 outpatients with active breast and gynecologic cancers recruited at the Gynecology Department of the Instituto Português de Oncologia de Coimbra Francisco Gentil. Cancer patients were divided into two groups: younger women <50 years and older women ≥50 years. Participants completed a socio-demographic questionnaire and self-report measures, namely Hospital Anxiety Depression Scale (HADS) and the six functional scales of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 (EORTC QLQ-C30). Our results show that the older group reported higher depressive symptoms than younger patients. Depressive symptoms influenced healthy functioning, defined by indicators such as physical, emotional and cognitive functioning, similarly in younger and older age groups.
Keywords
References
Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., . . . Haes, J. C. (1993). The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of life-instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85, 365-375.
Baker, F., Denniston, M., Smith, T., & West, M. M. (2005). Adult cancer survivors: How are they faring?. Cancer, 104, 2565-2576. doi: 10.1002/cncr.21488
Bower, J. E. (2008). Behavioral symptoms in patients with breast cancer and survivors. Journal of Clinical Oncology, 26, 768-777. doi: 10.1200/JCO.2007.14.3248
Bradley, S., Rose, S., Lutgendorf, S., Costanzo, E., & Anderson, B. (2006). Quality of life and mental health in cervical and endometrial cancer survivors. Gynecologic Oncology, 100, 479-486. http://dx.doi.org/10.1016/j.ygyno.2005.08.023
Bromberger, J. T., Matthews, K. A., Schott, L. L., Brockwell, S., Avis, N. E., Kravitz, H. M., . . . Randolph Jr, J. F. (2007). Depressive symptoms during the menopausal transition: The Study of Women’s Health Across the Nation (SWAN). Journal of Affective Disorders, 103, 267-272. doi: 10.1016/j.jad.2007.01.034
Cardoso, G., Graca, J., Klut, C., Trancas, B., & Papoila, A. (2015). Depression and anxiety symptoms following cancer diagnosis: A cross-sectional study. Psychology, Health & Medicine, 21, 562-570. doi: 10.1080/13548506.2015.1125006
Carter, J., Stabile, C., Gunn, A., & Sonoda, Y. (2013). The physical consequences of gynecologic cancer sugery and their impact on sexual, emotional and quality of life issues. The Journal of Sexual Medicine, 10, 21-34. doi: 10.1111/jsm.12002
Costa-Requena, G., Rodríguez, A., & Fernández-Ortega, P. (2013). Longitudinal assessment of distress and quality of life in the early stages of breast cancer treatment. Scandinavian Journal of Caring Sciences, 27, 77-83. doi: 10.1111/j.1471-6712.2012.01003.x
Costanzo, E. S., Ryff, C. D., & Singer, B. H. (2009). Psychosocial adjustment among cancer survivors: Findings from a national survey of health and well-being. Health Psychology, 28, 147-156. doi: 10.1037/a0013221
Ferlay, J., Soerjomataram, I., Ervik, M., Dikshit, R., Eser, S., Mathers, C., . . . Bray, F. (2013). GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. Lyon, France: International Agency for Research on Cancer. http://globocan.iarc.fr
Fiske, A., Wetherell, J. L., & Gatz, M. (2009). Depression in older adults. Annual Review of Clinical Psychology, 5, 363-389. doi: 10.1146/annurev.clinpsy.032408.153621
Gõmez-Campelo, P., Bragado-Álvarez, C., & Hernández-LIoreda, M. J. (2014). Psychological distress in women with breast and gynecological cancer treated with radical surgery. Psycho-Oncology, 23, 459-466. doi: 10.1002/pon.3439
Gorman, J., Malcarne, V., Roesch, S., Madlensky, L., & Pierce, J. (2010). Depressive symptoms among young breast cancer survivors: The importance of reproductive concerns. Breast Cancer Research and treatment, 123, 477-485. doi: 10.1007/s10549-010-0768-4
Hong, J. F., Zhang, W., Song, Y. X., Xie, L. F., & Wang, W. L. (2015). Psychological distress in elderly cancer patients. International Journal of Nursing Sciences, 2, 23-27. http://dx.doi.org/10.1016/j.ijnss.2015.02.006
Hu, L., & Bentler, P. M. (1999). Cutoff criteria for fit indexes in covariance structure analysis: Conventional criteria versus new alternatives. Structural Equation Modeling, 6, 1-55.
Hurria, A., Li, D., Hansen, K., Patil, S., Gupta, R., Nelson, C., . . . Kelly, E. (2009). Distress in older patients with cancer. Journal of Clinical Oncology, 27, 4346-4351. doi: 10.1200/JCO.2008.19.9463
Jadoon, N. A., Munir, W., Shahzad, M. A., & Choudhry, Z. S. (2010). Assessment of depression and anxiety in adult cancer outpatients: A cross sectional study. BMC Cancer, 10. doi: 10.1186/1471-2407-10-594
Krok, J. L., Baker, T. A., & McMillan, S. C. (2013). Age differences in the presence of pain and psychological distress in younger and older cancer patients. Journal of Hospice & Palliative Nursing, 15, 107-113. doi: 10.1097/NJH.0b013e31826bfb63
Leach, C. R., Bellizzi, K. M., Hurria, A., & Reeve, B. B. (2016). Is it my cancer or am I just getting older?: Impact of cancer on age-related health conditions of older cancer survivors. Cancer, 122, 1946-1953. doi: 10.1002/cncr.29914
MacCallum, R. C., Browne, M. W., & Sugawara, H. M. (1996). Power analysis and determination of sample size for covariance structure modeling. Psychological Methods, 1, 130-149.
McMillan, S. C., & Small, B. J. (2002). Symptom distress and quality of life in patients with cancer newly admitted to hospice home care. Oncology Nursing Forum, 29, 1421-1428. doi: 10.1188/02.ONF.1421-1428
Montazeri, A. (2008). Health-related quality of life in breast cancer patients: A bibliographic review of the literature from 1974 to 2007. Journal of experimental & Clinical Cancer Research, 29, 32. doi: 10.1186/1756-9966-27-32
Nelson, C. J., Weinberger, M. I., Balk, E., Holland, J., Breitbart, W., & Roth, A. J. (2009). The chronology of distress, anxiety, and depression in older prostate cancer patients. The oncologist, 14, 891-899. doi: 10.1634/theoncologist.2009-0059
Pais-Ribeiro, J., Pinto, C., & Santos, C. (2008). Estudo de validação da versão portuguesa do QLQ-C30-V.3. Psicologia, Saúde & Doenças, 9, 89-102.
Pais-Ribeiro, J., Silva, I., Ferreira, T., Martins, A., Meneses, R., & Baltar, M. (2007). Validation study of a Portuguese version of the Hospital Anxiety and Depression Scale. Psychology, Healthy & Medicine, 12, 225-237. doi: 10.1080/13548500500524088
Park, B. W., Lee, S., Lee, A. R., Lee, K. H., & Hwang, S. Y. (2011). Quality of life differences between younger and older breast cancer patients. Journal of Breast Cancer, 14, 112-118. doi: 10.4048/jbc.2011.14.2.112
Quinten, C., Coens, C., Ghislain, I., Zikos, E., Sprangers, M. A., Ringash, J., . . . Bottomlev, A. (2015). The effects of age on health-related quality of life in cancer populations: A pooled analysis of randomized controlled trials using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 involving 6024 cancer patients. European Journal of Cancer, 51, 2808-2819. doi: 10.1016/j.ejca.2015.08.027
Reyes-Gibby, C. C., Anderson, K. O., Morrow, P. K., Shete, S., & Hassan, S. (2012). Depressive symptoms and health-related quality of life in breast cancer survivors. Journal of Women’s Health, 21, 311-318. doi: 10.1089/jwh.2011.2852
Rosenberg, S. M., & Patridge, A. H. (2013). Premature menopause in young breast cancer: Effects on quality of life and treatment interventions. Journal of Thoracic Disease, 5, S55-S61. doi: 10.3978/j.issn.2072-1439.2013.06.20
Sant, M., Capocaccia, R., Coleman, M. P., Berrino, F., Gatta, G., Micheli, A., Verdecchia, A., . . . EROCARE Working Group. (2001). Cancer survival increases in Europe, but international differences remain wide. European Journal of Cancer, 37, 1659-1667.
Schapmire, T. J., & Faul, A. C. (in press). Depression symptoms in older adults with cancer: A multilevel longitudinal study. Journal of Psychosocial Oncology. doi: 10.1080/07347332.2017
Wenzel, L., Dogan-Ates, A., Habbal, R., Berkowitz, R., Goldstein, D. P., Bernstein, M., . . . Cella, D. (2005). Defining and measuring reproductive concerns of female cancer survivors. Jornal of the National Cancer Institute Monographs, 34, 94-98. doi: 10.1093/jncimonographs/lgi017
Zigmond, A. P., & Snaith, R. P. (1983). The Hospital Anxiety and Depression Scale. Acta Psychiatrica Scandinavica, 67, 361-370.
DOI: https://doi.org/10.14417/ap.1345
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